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P117.ACUTE PULMONARY EMBOLISM IN CHRONIC
OBSTRUCTIVE PULMONARY DISEASE: WHAT
PARTICULARITIES?
H. ZAIBI , M. KHEDRI, E. BEN JEMIA, H. OUERTANI, K. CHAABI, E. NEMSI, J. BEN AMAR
, H. AOUINA
SERVICE DE PNEUMOLOGIE DE L'HOPITAL CHARLES NICOLLE DE TUNIS
INTRODUCTION : Chronic Obstructive Pulmonary Disease (COPD) is an
established cause of worse evolution during acute Pulmonary Embolism (PE). What
about our Tunisian patients?
Aim: To study the PE particularities in Chronic Obstructive Pulmonary Disease
(COPD) in a Tunisian population.
Methods: We conducted a retrospective cohort study in consecutive patients
diagnosed with PE between 2005 and 2023. We compared COPD to No COPD
patients.
Results: Among 182 included patients, 31 (17%) had COPD. Most of them were
elderly (mean age: 66 vs 52 years in patients without COPD, p<0.001). COPD patients
were mostly male (87% vs 12%, p=0.001). Smoking was more important in COPD
patients (p=0.003). They were more likely to have comorbidities (p=0.09) and
dyspnea (p=0.02) as functional complaint. They also had more respiratory struggles
signs (p=0.03), right signs in electrocardiogram (p=0.02) and hypercapnia (p=0.0001).
EP was more severe in COPD patients with a higher PESI score (p<0.0001). COPD
was significantly associated with right heart failure and prolonged hospital stay
(p=0.05).
CONCLUSION: The number of COPD patients diagnosed for acute PE was lightly
higher than previously reported. In addition, COPD patients might be an
underrecognized group with increased severity and morbidity
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