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P117.ACUTE              PULMONARY               EMBOLISM             IN     CHRONIC
               OBSTRUCTIVE                    PULMONARY                   DISEASE:              WHAT

               PARTICULARITIES?

               H. ZAIBI , M. KHEDRI, E. BEN JEMIA, H. OUERTANI, K. CHAABI, E. NEMSI, J. BEN AMAR
               , H. AOUINA
               SERVICE DE PNEUMOLOGIE DE L'HOPITAL CHARLES NICOLLE DE TUNIS


               INTRODUCTION  :  Chronic Obstructive Pulmonary  Disease (COPD) is an
               established cause of worse evolution during acute Pulmonary Embolism (PE). What
               about our Tunisian patients?
               Aim:  To study the PE particularities in Chronic Obstructive Pulmonary  Disease
               (COPD) in a Tunisian population.

               Methods: We  conducted  a retrospective  cohort  study in  consecutive patients
               diagnosed with PE between 2005  and 2023. We  compared COPD to No COPD
               patients.

               Results:  Among 182 included patients, 31  (17%) had COPD. Most  of them  were
               elderly (mean age: 66 vs 52 years in patients without COPD, p<0.001). COPD patients
               were mostly male (87% vs 12%, p=0.001). Smoking was more important in COPD
               patients  (p=0.003). They  were more likely  to have comorbidities (p=0.09)  and
               dyspnea (p=0.02) as functional complaint. They also had more respiratory struggles
               signs (p=0.03), right signs in electrocardiogram (p=0.02) and hypercapnia (p=0.0001).
               EP was more severe in COPD patients with a higher PESI score (p<0.0001). COPD
               was  significantly  associated with right heart  failure  and prolonged  hospital stay
               (p=0.05).

               CONCLUSION: The number of COPD patients diagnosed for acute PE was lightly
               higher  than  previously reported. In addition, COPD patients might  be an
               underrecognized group with increased severity and morbidity






























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