Page 39 - Livre électronique des RFTP 2023
P. 39

CONCLUSION : Mucositis toxicity is dose-dependent and occurs at higher doses.
               Mucositis and mucosal erosions are caused by the suppressive effect of MTX on
               cell proliferation. As highly replicative cells are affected more severely than cells
               of non-proliferative or  weakly  proliferative tissues, mucositisis  one of the most
               common side effects of high-dose MTX  therapy.














































































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