Page 33 - Livre électronique des RFTP 2023

P9. ASSOCIATION BETWEEN ASTHMA CONTROL AND

PULMONARY FUNCTION

B.BARKOUS, K.KCHAOU, C.BRIKI, S.JAMLI, S.BEN KHAMSA JAMELEDDINE

DEPARTMENT OF PHYSIOLOGY AND FUNCTIONALRESPIRATORY EXPLORATIONS, ABDERRAHMANE
MAMI HOSPITAL ARIANA, TUNISIA.

INTRODUCTION : Evaluating the degree of disease control is pivotal in asthmatic
patients. Asthma control is defined as the degree to which manifestations of the
disease are reduced or removed by therapy.

OBJECTIVE : To investigate the association between asthma control and
respiratory function.

PATIENTS AND METHODS : It was a cross-sectional study, including 62 asthmatic
patients, conducted in the department of Pulmonary Function Testing of
Abderrahmane Mami hospital Ariana. All patients underwent spirometry with
measurement of Forced Expiratory Volume in one second (FEV1), Forced Vital
Capacity (FVC), Peak Expiratory Flow (PEF), Forced Expiratory Flow (FEF25-75%)
and answered the Asthma Control Questionnaire (ACQ).

RESULTS : Mean age (years) was 62.68±1.83. There was a female predominance
with 67.7%. Dyspnea was present in 72.4% of patients and graded according to
mMRC scale as follows: mMRC 1 (41.4%), mMRC 2 (12.1%), mMRC 3 (15.5%) and mMRC
4 (3.4%). forty-five percent of patients had controlled asthma. ACQ was correlated
with FEV1% (p<0.05, r= -0.413), FEV1/FVC ratio (p<0.05, r= -0.419), PEF (p<0.05, r= -
0.389) and FEF25-75% (p<0.05, r= -0.368). ROC analysis was conducted and showed
that FEV1% was the best predictor of asthma control (Area Under Curve
[AUC]=0.712, CI:0.55-0.874).

CONCLUSION : Monitoring asthma control is crucial to guide asthma
management decisions. Subjective tools such as ACQ and objective measures
such as spirometry were correlated in this study and FEV1% seems to be the best
predictor of asthma control.

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